India’s Firsts 2025–26: Ultimate Science and Technology Notes

India's Firsts 2025–26: Ultimate Science and Technology Notes

World’s first nuclear heat-based Cu–Cl thermochemical hydrogen production facility → IGCAR Kalpakkam

  • Cu–Cl = Copper–Chlorine Thermochemical Cycle.
  • World’s first such facility → India.
  • Uses heat from FBTR.
  • Technology developed by BARC.
  • Facility located at IGCAR, Kalpakkam.
  • FBTR supports India’s Stage-II Nuclear Programme.
  • PFBR = 500 MWe Fast Breeder Reactor.
  • World’s first facility integrating nuclear heat + Cu–Cl hydrogen production.

Coal-to-Ammonium Nitrate Project

  • India’s first commercial Coal-to-Ammonium Nitrate plant → Lakhanpur (Odisha).
  • Developed by Bharat Coal Gasification and Chemicals Limited.
    • Joint Venture:
      • Bharat Heavy Electricals Limited
      • Coal India Limited
  • Uses indigenously developed coal gasification technology by BHEL.
  • Output → 2,000 TPD Ammonium Nitrate.
  • Coal Gasification produces Syngas.
  • Incentive Scheme Outlay → ₹46,000 crore.
  • India has 5th largest coal reserves globally.

SkyCast → India’s first integrated aviation weather monitoring system (IGI Airport, Delhi).

  • Developed Under: Mission Mausam
  • Ministry of Earth Sciences (MoES)
  • Installed At: Indira Gandhi International Airport (IGI), New Delhi
  • Next Location: Jewar Airport (Noida International Airport), Uttar Pradesh

BIRSA-101 → India’s first indigenous CRISPR-based gene therapy for Sickle Cell Disease.

  • Developed by CSIR-Institute of Genomics and Integrative Biology.
  • Technology transferred to Serum Institute of India.
  • Based on CRISPR gene-editing technology.
  • Public–Private Partnership (PPP) model.
  • Focus: Affordable genomic therapies for underserved populations.
  • Beneficiaries: Tribal communities of Central & Eastern India.

DHRUV64 → India’s first 1.0 GHz, 64-bit dual-core microprocessor.

  • Developed by Centre for Development of Advanced Computing.
  • Developed under Microprocessor Development Programme (MDP).
  • Fully indigenous processor.
  • Based on RISC-V architecture.
  • DIR-V Programme
  • Digital India RISC-V (DIR-V)
    • Launched: 2022
    • Objective:
      • Develop indigenous RISC-V processors.
      • Make India a global ESDM hub.
    • DHRUV64 developed under this ecosystem.

BharatGen → India’s first sovereign multilingual & multimodal AI LLM.

  • India’s first sovereign multilingual & multimodal Large Language Model (LLM).
  • Launched/reviewed at Indian Institute of Technology Bombay.
  • Expanded under IndiaAI Mission.

QSIP → India’s Quantum Security Chip.

25-Qubit QPU → India’s first Quantum Processing Unit.

Animal Stem Cell Biobank → First-of-its-kind facility at Hyderabad.

  • India’s first Animal Stem Cell Biobank & Animal Stem Cell Laboratory inaugurated at National Institute of Animal Biotechnology.
  • Supported by DBT-BIRAC’s National Biopharma Mission.

Quantum & AI University → First dedicated campus at Amaravati.

  • Implementing Institution → NIELIT.
  • Linked to Andhra Quantum Mission.
  • Quantum Valley = Andhra Pradesh’s quantum ecosystem initiative.
  • NIELIT is a Deemed-to-be University under MeitY.

Chip Fabrication Plant → India’s first semiconductor fab at Dholera, Gujarat.

  • Spearheaded by Tata Electronics in a strategic partnership with Taiwan’s Powerchip Semiconductor Manufacturing Corporation (PSMC), the facility represents an investment of over ₹91,000 crore.

OSAT Pilot Line → One of India’s first end-to-end semiconductor packaging facilities at Sanand.

  • OSAT = Outsourced Semiconductor Assembly and Test.
  • India’s first end-to-end OSAT pilot line → Sanand, Gujarat.
  • Investment → ₹7,600 crore.
  • G1 Capacity → 0.5 million units/day.
  • G2 Capacity → 14.5 million units/day.

India’s First Liquid Helium Cryogenic Facility

  • Inaugurated at Indian Institute of Technology Bombay.
  • Supports quantum technologies, superconductivity and advanced scientific research.

India’s First MWh-Scale Vanadium Flow Battery

  • Commissioned at NTPC NETRA (Greater Noida).
  • Long-duration energy storage technology.
  • Useful for renewable energy integration.

. India’s First Indigenously Discovered Antibiotic – Nafithromycin (Miqnaf)

  • India’s first indigenous Macrolide Antibiotic launched.
  • Developed by Wockhardt.
  • Supported by Biotechnology Industry Research Assistance Council.

India’s First Internationally Recognised Equine Disease-Free Compartment

  • EDFC located at Meerut, Uttar Pradesh.
  • Recognised by WOAH.
  • India free from African Horse Sickness since 2014.
  • Glanders and Surra are important equine diseases.
  • Compartmentalisation is a WOAH-approved biosecurity approach.

India’s first indigenous high-precision compact diode laser demonstrated

  • Developed by Prenishq Pvt Ltd.
  • Supported under National Quantum Mission.
  • Origin: Spin-off from Indian Institute of Technology Delhi.
  • Covers UV to Near-Infrared wavelengths.
  • Enables Quantum Encrypted Communication.
  • Important component for photonic quantum computers.

Read More: Major Facts About India