World’s first nuclear heat-based Cu–Cl thermochemical hydrogen production facility → IGCAR Kalpakkam
- Cu–Cl = Copper–Chlorine Thermochemical Cycle.
- World’s first such facility → India.
- Uses heat from FBTR.
- Technology developed by BARC.
- Facility located at IGCAR, Kalpakkam.
- FBTR supports India’s Stage-II Nuclear Programme.
- PFBR = 500 MWe Fast Breeder Reactor.
- World’s first facility integrating nuclear heat + Cu–Cl hydrogen production.
Coal-to-Ammonium Nitrate Project
- India’s first commercial Coal-to-Ammonium Nitrate plant → Lakhanpur (Odisha).
- Developed by Bharat Coal Gasification and Chemicals Limited.
- Joint Venture:
- Bharat Heavy Electricals Limited
- Coal India Limited
- Joint Venture:
- Uses indigenously developed coal gasification technology by BHEL.
- Output → 2,000 TPD Ammonium Nitrate.
- Coal Gasification produces Syngas.
- Incentive Scheme Outlay → ₹46,000 crore.
- India has 5th largest coal reserves globally.
SkyCast → India’s first integrated aviation weather monitoring system (IGI Airport, Delhi).
- Developed Under: Mission Mausam
- Ministry of Earth Sciences (MoES)
- Installed At: Indira Gandhi International Airport (IGI), New Delhi
- Next Location: Jewar Airport (Noida International Airport), Uttar Pradesh
BIRSA-101 → India’s first indigenous CRISPR-based gene therapy for Sickle Cell Disease.
- Developed by CSIR-Institute of Genomics and Integrative Biology.
- Technology transferred to Serum Institute of India.
- Based on CRISPR gene-editing technology.
- Public–Private Partnership (PPP) model.
- Focus: Affordable genomic therapies for underserved populations.
- Beneficiaries: Tribal communities of Central & Eastern India.
DHRUV64 → India’s first 1.0 GHz, 64-bit dual-core microprocessor.
- Developed by Centre for Development of Advanced Computing.
- Developed under Microprocessor Development Programme (MDP).
- Fully indigenous processor.
- Based on RISC-V architecture.
- DIR-V Programme
- Digital India RISC-V (DIR-V)
- Launched: 2022
- Objective:
- Develop indigenous RISC-V processors.
- Make India a global ESDM hub.
- DHRUV64 developed under this ecosystem.
BharatGen → India’s first sovereign multilingual & multimodal AI LLM.
- India’s first sovereign multilingual & multimodal Large Language Model (LLM).
- Launched/reviewed at Indian Institute of Technology Bombay.
- Expanded under IndiaAI Mission.
QSIP → India’s Quantum Security Chip.
25-Qubit QPU → India’s first Quantum Processing Unit.
Animal Stem Cell Biobank → First-of-its-kind facility at Hyderabad.
- India’s first Animal Stem Cell Biobank & Animal Stem Cell Laboratory inaugurated at National Institute of Animal Biotechnology.
- Supported by DBT-BIRAC’s National Biopharma Mission.
Quantum & AI University → First dedicated campus at Amaravati.
- Implementing Institution → NIELIT.
- Linked to Andhra Quantum Mission.
- Quantum Valley = Andhra Pradesh’s quantum ecosystem initiative.
- NIELIT is a Deemed-to-be University under MeitY.
Chip Fabrication Plant → India’s first semiconductor fab at Dholera, Gujarat.
- Spearheaded by Tata Electronics in a strategic partnership with Taiwan’s Powerchip Semiconductor Manufacturing Corporation (PSMC), the facility represents an investment of over ₹91,000 crore.
OSAT Pilot Line → One of India’s first end-to-end semiconductor packaging facilities at Sanand.
- OSAT = Outsourced Semiconductor Assembly and Test.
- India’s first end-to-end OSAT pilot line → Sanand, Gujarat.
- Investment → ₹7,600 crore.
- G1 Capacity → 0.5 million units/day.
- G2 Capacity → 14.5 million units/day.
India’s First Liquid Helium Cryogenic Facility
- Inaugurated at Indian Institute of Technology Bombay.
- Supports quantum technologies, superconductivity and advanced scientific research.
India’s First MWh-Scale Vanadium Flow Battery
- Commissioned at NTPC NETRA (Greater Noida).
- Long-duration energy storage technology.
- Useful for renewable energy integration.
. India’s First Indigenously Discovered Antibiotic – Nafithromycin (Miqnaf)
- India’s first indigenous Macrolide Antibiotic launched.
- Developed by Wockhardt.
- Supported by Biotechnology Industry Research Assistance Council.
India’s First Internationally Recognised Equine Disease-Free Compartment
- EDFC located at Meerut, Uttar Pradesh.
- Recognised by WOAH.
- India free from African Horse Sickness since 2014.
- Glanders and Surra are important equine diseases.
- Compartmentalisation is a WOAH-approved biosecurity approach.
India’s first indigenous high-precision compact diode laser demonstrated
- Developed by Prenishq Pvt Ltd.
- Supported under National Quantum Mission.
- Origin: Spin-off from Indian Institute of Technology Delhi.
- Covers UV to Near-Infrared wavelengths.
- Enables Quantum Encrypted Communication.
- Important component for photonic quantum computers.
Read More: Major Facts About India



